Position Description:

Every great life-changing discovery begins the same way-with new knowledge. It can change everything, from a single life to the future of entire communities. That's why academic medicine, and the continuous pursuit of knowledge, is at the center of everything we do at the Medical College of Wisconsin (MCW).

In the role of Research Associate I you will, under minimal supervision, use fundamental concepts, practices, and procedures of particular field of specialization to perform complex scientific research.

This role will be in the laboratory of Dr. William Drobyski in the Departments of Medicine and Microbiology at the Medical College of Wisconsin that is focused on transplantation immunology with a specific emphasis on the immunobiology of allogeneic bone marrow transplantation and the pathophysiology of graft versus host disease (GVHD). Other areas of interest emanating from this focus include T cell and regulatory T cell biology along with inflammation induced by innate immune cells (macrophages, microglia, and dendritic cells).

Specific areas of interest include inflammatory cytokine networks that contribute to GVHD, inflammatory cytokine signaling and regulatory pathways that impact the development of tolerance, modulate anti-leukemic responses, and induce pathological damage particularly within the gastrointestinal tract and central nervous system using genetically modified mouse models, flow cytometry, q-PCR, RNA-seq, western blot, single cell RNA seq, bioinformatics, and other immunological techniques. Recent publications include Journal of Clinical Investigation 2016; 126: 3541-3555, Blood 2018; 132(4): 435-447, Nature Communications 2018; 9(1): 5037; Blood 2020; 135(8): 568-581, Blood 2021; 137(9): 1241-1255, and Blood Advances 2022; 6(9): 2791-2803.

Responsibilities:

• Perform immunology experiments from design conception to final data analysis and presentation of results with minimal supervision.
• Collect, analyze and provide summations of data from experiments. Perform all necessary calculations and reduction of data errors to allow for interpretation of all experimental outcomes.
• Prepare scientific papers and assist the Principal Investigator in the preparations of manuscripts.
• Perform molecular biological assays using RT-PCR, real time PCR, Western and molecular cloning techniques. Adopt new techniques in laboratory.
• Coordinate research study activities. Assist in developing, implementing and monitoring quality activities.
• Participate in meetings with principle investigator and research staff and evaluate/interpret the validity of data, develop methodologies, evaluate lab procedures.
• Manage and operate lab equipment.
• Train new employees in lab procedures

Knowledge - Skills - Abilities

• Experience with flow cytometry, ELISA, western and molecular cloning techniques, immunohistochemical staining.
• Experience with the appropriate means of handling of laboratory animals is required.
• Knowledge of biology, chemistry, mathematics, documentation, and records management.
• Data utilization, complex problem solving, critical thinking, resource management, and writing skills.

Preferred Schedule: Full-time role with expectations for coverage during core business hours and flexibility required as necessary to accommodate business needs.

Position Requirements:

Minimum Qualifications:Appropriate experience may be substituted for education on an equivalent basis

• Master's degree
• No experience required.

Preferred Qualifications:

• Master's or PhD degree
• Immunology, including mouse models, flow cytometry and/or molecular biology, and bioinformatics.

Why MCW?

• Outstanding Healthcare Coverage, including but not limited to Health, Vision, and Dental. Along with Flexible Spending options
• 403B Retirement Package
• Competitive Vacation and Paid Holidays offered
• Tuition Reimbursement
• Paid Parental Leave
• Pet Insurance
• On campus Fitness Facility, offering onsite classes.
• Additional discounted rates on items such as: Select cell phone plans, local fitness facilities, Milwaukee recreation and entertainment etc.

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For a brief overview of our benefits see:

Eastern Wisconsin is a vibrant, diverse metropolitan area. MCW is intent on attracting, developing, and retaining a diverse workforce and faculty body that reflects the community we serve. We value diversity of backgrounds, experience, thought, and perspectives to advance excellence in science and medicine. MCW is a welcoming campus community with a strong culture of collaboration, partnership, and engagement with our surrounding community. For more information, please visit our institutional website at #LI-AC1